comprex® and Endoprime
comprex Medical GmbH is a company of the Hammann Group and uses the proven comprex® process specifically for the medical industry. With Endoprime we offer an innovative solution for the cleaning of media-carrying systems in medical facilities.
With comprex®, we can easily remove deposits such as dried blood, tissue remnants or biofilm from the endoscope channels. This process is much more efficient and hygienic than conventional cleaning with brushes.
The comprex® process
The patented cleaning process with pulses of air and water
We have been researching, testing and patenting our comprex® process for almost three decades. As a service provider for cleaning and as a manufacturer of mobile and stationary cleaning systems, we are active in various areas and sectors of drinking water supply and industry.
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We have received the intention to grant a European unitary patent for our innovative comprex® Medical cleaning process.
This intention to grant no. 22 199 043.5 dated 05.04.2025 relates to a method and device for cleaning medical instruments using modulating pressurised gas pulses.
Patents protect our innovations and confirm our technological lead.
Welcome at comprex® Medical.
We are developing the first automated endoscope pre-cleaning system!
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The reprocessing of flexible endoscopes is a major challenge in the daily routine of practices and clinics. To ensure correct cleaning, a complex workflow is required.
Until today the pre-cleaning process has been carried out manually with brushes by specialist staff. But the unpredictability of the ‚human factor‘ leads to the urgent request to replace this manual cleaning by an automated mechanical process prior to high-level disinfection.
Moreover, manual pre-cleaning of endoscopes with brushes takes a huge effort concerning labour and time. It is economically inefficient. Besides this, work steps performed manually are difficult to validate and provide an increased risk of contamination for the patient, staff and environment.
But: patients need safety. Users and doctors need simplicity and routine in every work step.
Above all, we need a simple solution that minimises time, effort, costs and risk.
Automated endoscope pre-cleaning
Endoprime: Easy cleaning with one device
Our mission: With the patented impulse flushing method we want to set a new standard of hygiene in the medical sector. Our cleaning technology is validatable, efficient and sustainable.
Validatable
Validatable and automated
pre-cleaning
of all ducts with pressure testing
Mechanical
Water and air pulses replace
the manual
brush cleaning
Secure
Reproducible results through
cleaning
recipes and documentation
Flexible
Can be integrated into existing
cleaning processes and systems
Economical
Reduced fluid consumption,
Savings in cleaning agents and
disposable products
Clean
Cleaning is carried out continuously with fresh
water and the discharge is carefully separated
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To clean the endoscope channels we are using the patented impulse flushing technology comprex®.
The manual cleaning steps of endoscope channels are replaced and simplified in our process.
The user is guided through all process steps. The cleaning results are reproducible and validatable. This user-friendly process ensures the safety for patients and clinics.
This includes:
1. Digital registration of users and endoscopes
2. Automatic leakage test
3. Cleaning and flushing of all channels with fresh water and separated discharge
4. Digital documentation
Our areas of application are municipal pipelines and networks, drinking water installations in buildings, and industrial systems. If deposits form in the pipes, we are there to remove them. The focus of our services is the patented COMPREX® impulse flushing process developed by us, which we are constantly redefining and expanding in various performance levels. This enables us to adapt it perfectly to the individual, changing tasks of our customers.
The development of comprex® Medical
The story behind
Our story began in 2005 when Paulina Lämmer first contacted the Institute for Hygiene and Public Health at the University of Bonn under the direction of Prof. Dr. med. Martin Exner. In an expert opinion, he confirmed the cleaning performance of the comprex® process using his biofilm silicone tube model.
This resulted in our participation in a first BMBF research project on biofilms in domestic installations under the leadership of Prof. Dr. Hans-Curt Flemming (University of Duisburg-Essen), Prof. Dr. med. Martin Exner and Dr. Jürgen Gebel, who has been our contact person for studies and research ever since.
This was followed by further research projects and the development of special test systems that were used at the Bonn Institute to clean endoscope dummies. Two dissertations from 2014 and 2018, supervised by Prof. Dr. med. Martin Exner, once again confirmed the exceptional cleaning performance of comprex®.
As a budding physicist, Paulina Lämmer was actively involved in the project for brushless Cleaning of PTFE Test Pieces as a Surrogate of Endoscope Channels. Her scientific contribution laid the foundation for the development of Endoprime.
The promising results of this research encouraged us to press ahead with the development of a user-friendly device for the automated reprocessing of flexible endoscopes.
Observations in surgeries and clinics as well as numerous discussions with medical professionals
O confirmed that there is a great need for a simple, hygienic solution that replaces manual brush cleaning.
Some of the research results were recently published in the journal Hygiene & Medizin. Find the article here:
In collaboration with VanVliet, which has been in place since 2023, Endoprime is now being produced in pre-series and will be tested in a pilot series in hospitals in Germany and the Netherlands from the second quarter of 2025. It is planned that Endoprime will be available on the market in early 2026.
Paulina Lämmer has now retired from comprex Medical GmbH and has been working full-time in another company in the regulatory area since the end of 2024.
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The comprex® process
The patented cleaning process with pulses of air and water
For more than 28 years we have developed and improved our technology and received the patent for comprex®. As a service provider and as a manufacturer of mobile and stationary cleaning systems, we are active in various areas of drinking water supply and industry.
With comprex we can easily remove deposits such as dried blood, tissue residues or biofilm from the endoscope channels. This process is way much more efficient and hygienic compared to brush cleanin
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Contact
This is us
Hans-Gerd Hammann
CEO Hammann GmbH | comprex®
hg.hammann@comprex.de
+49 6346 3004-44
Vincent Hammann
CEO Hammann GmbH | comprex®
v.hammann@comprex.de
+49 6341 38084-75
Hans-Gerd and Vincent Hammann lead Hammann GmbH, the sole owner of comprex Medical GmbH. Using the comprex® process, the company developed Endoprime for the medical sector. In partnership with Van Vliet Medical since 2023, Endoprime is now in pre-series production and will be tested in hospitals in Germany and the Netherlands from Q2 2025, with market launch planned for early 2026.
Van Vliet Medical
Kooperationspartner
In 1985, Van Vliet Medical embarked on a remarkable journey, starting from a humble kitchen table in Weesp, the Netherlands. Fueled by a passion for innovation, our initial focus was the development of a bedpan washer-disinfector. Little did we know that this ingenuity would be the foundation of our success.
As our aspirations grew, so did our headquarters, now situated in a spacious building in Almere, The Netherlands. The visionary concept of the bedpan washer-disinfector quickly became a reality, followed closely by the introduction of our renowned endoscope drying cabinets.
Over the years, we have evolved into a comprehensive solution provider, catering to the diverse needs of healthcare institutions. Equipped with our own technical department, we proudly offer an array of products designed exclusively for medical use.
As we progress forward, our passion for innovation remains at the forefront of everything we do. Stay tuned, as we continue to make strides in revolutionizing medical equipment, all while ensuring the utmost quality and customer satisfaction.
The cooperation between Van Vliet Medical and comprex® is an important step to scale the production and distribution of Endoprime® worldwide and to ensure highest quality and customer satisfaction.
